Manchester United have accepted a bid from Real Betis to sign Antony in a permanent deal.
The winger has been given permission to travel to Seville to finalise the move after he spent the second half of last season on loan at the Spanish side.
It is now up to Antony and Real Betis to agree personal terms.
Antony was signed from Ajax for £86m in the summer of 2022
United had made it clear in negotiations with Real Betis that they did not want to do another straight loan for the 25-year-old.
Sky Sports News has previously reported that Antony had attracted interest from the Saudi Pro League.
Atletico Madrid, Bayer Leverkusen and Bayern Munich have also monitored his situation.
But, despite having other offers, Antony has made it clear he wanted to return to Betis.
The Brazil international had an impressive loan spell there in the second half of last season, scoring nine goals in 24 starts.
If Antony completes a permanent move to Betis it would end a forgettable three years at Man Utd, whom he joined for £86m from Ajax.
Antony failed to justify his price tag at Old Trafford as he scored just 12 goals in 96 appearances across all competitions.
Garnacho set for Chelsea move
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Enzo Maresca confirmed Alejandro Garnacho was at the Chelsea training ground and he expects him to fit into the Blues squad as a winger
Antony is set to follow Alejandro Garnacho out of Man Utd after Chelsea agreed a £40m deal to sign the winger.
The 21-year-old forward underwent his Chelsea medical on Friday.
The deal, which includes a 10 per cent sell-on fee, represents the fourth-largest sale in United’s history after those of Cristiano Ronaldo, Romelu Lukaku and Angel Di Maria – and the club’s largest-ever sale of an academy graduate.
A compromise over Garnacho’s valuation had to be reached as United valued him at £50m – which was more than Chelsea were prepared to pay.
United negotiated the fee up from an initial Chelsea offer of £25m and are understood to feel it is a good, pragmatic deal, delivering their largest sale fee for five years. They also believe it is a good solution for the player, who has been pushing strongly to leave.
Mainoo tells Man Utd he wants to leave
Kobbie Mainoo has expressed an interest to leave on loan
Kobbie Mainoo has requested a loan move to get more game time this season, Sky Sports News has been told.
But United have no intention of allowing him to go on loan and Ruben Amorim insisted on Friday that he wants the 20-year-old to stay.
Amorim said: “I want Kobbie to stay and he needs to fight for his place. We need Kobbie. That is not going to change.”
Meanwhile, Napoli are hopeful Rasmus Hojlund will travel to Naples for a medical in the next few days.